Assay Detail
Binding
CHEMBL973662
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Inhibition of ribosomal activity in erythromycin-sensitive Propionibacterium acnes EG7NS assessed as luciferase production by transcriptional and translational assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cutibacterium acnes |
| Subcellular | Ribosome |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Activity of the novel macrolide BAL19403 against ribosomes from erythromycin-resistant Propionibacterium acnes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.87 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405863 | — | — | 1 | 6.96 |
| CHEMBL532 | ERYTHROMYCIN | 4.0 | 1 | 6.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405863 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL532 | ERYTHROMYCIN | IC50 | = | 170.0 | nM | 6.77 |