Assay Detail
Binding
CHEMBL973892
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Inhibition of prolyl endopeptidase
9
Total Activities
9
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Bioactive constituents from Boswellia papyrifera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.79 | 5.54 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL499293 | — | — | 1 | 5.54 |
| CHEMBL237111 | AKBA | -1.0 | 1 | 5.10 |
| CHEMBL267225 | BOSWELLIC ACID | 2.0 | 1 | 5.01 |
| CHEMBL437964 | 11-KETO BOSWELLIC ACID | — | 1 | 4.44 |
| CHEMBL566929 | BETA-ELEMONIC ACID | — | 1 | 4.40 |
| CHEMBL449310 | — | — | 1 | 4.24 |
| CHEMBL236075 | — | — | 1 | - |
| CHEMBL501898 | — | — | 1 | - |
| CHEMBL477753 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL499293 | — | IC50 | = | 2866.0 | nM | 5.54 |
| CHEMBL237111 | AKBA | IC50 | = | 7890.0 | nM | 5.10 |
| CHEMBL267225 | BOSWELLIC ACID | IC50 | = | 9750.0 | nM | 5.01 |
| CHEMBL437964 | 11-KETO BOSWELLIC ACID | IC50 | = | 36320.0 | nM | 4.44 |
| CHEMBL566929 | BETA-ELEMONIC ACID | IC50 | = | 39740.0 | nM | 4.40 |
| CHEMBL449310 | — | IC50 | = | 57430.0 | nM | 4.24 |
| CHEMBL236075 | — | IC50 | = | 114750.0 | nM | - |
| CHEMBL501898 | — | Activity | - | — | - | |
| CHEMBL477753 | — | Activity | - | — | - |