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Assay Detail

CHEMBL973957

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat DNA polymerase beta in presence of BSA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

DNA polymerase beta (CHEMBL4343)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Harbinatic acid, a novel and potent DNA polymerase beta inhibitor from Hardwickia binata.
Deng JZ, Starck SR, Hecht SM, Ijames CF, Hemling ME.
J Nat Prod (1999) 62 : 1000 -1002
PubMed 10425125 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.33 5.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL494656 HARBINATIC ACID 1 5.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL494656 HARBINATIC ACID IC50 = 4700.0 nM 5.33