Assay Detail
Binding
CHEMBL974511
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Displacement of [14C]ERY from erythromycin-sensitive Escherichia coli BL21 ribosome
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli BL21 |
| Subcellular | Ribosome |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Activity of the novel macrolide BAL19403 against ribosomes from erythromycin-resistant Propionibacterium acnes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.77 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL532 | ERYTHROMYCIN | 4.0 | 1 | 7.96 |
| CHEMBL405863 | — | — | 1 | 7.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL532 | ERYTHROMYCIN | Kd | = | 11.0 | nM | 7.96 |
| CHEMBL405863 | — | Kd | = | 26.0 | nM | 7.58 |