Assay Detail
Functional
CHEMBL975113
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Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
seco-Cycloartane triterpenes from Gardenia aubryi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.45 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1563 | DAUNORUBICIN HYDROCHLORIDE | 4.0 | 1 | 6.50 |
| CHEMBL2332132 | SECAUBRYOLIDE | — | 1 | 4.40 |
| CHEMBL523126 | SECAUBRYENOL | — | 1 | - |
| CHEMBL491709 | SECAUBRYTRIOL | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1563 | DAUNORUBICIN HYDROCHLORIDE | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL2332132 | SECAUBRYOLIDE | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL523126 | SECAUBRYENOL | IC50 | > | 100000.0 | nM | - |
| CHEMBL491709 | SECAUBRYTRIOL | IC50 | > | 100000.0 | nM | - |