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Assay Detail

CHEMBL975560

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat CAO
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [copper-containing] 3 (CHEMBL4592)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Fluorinated phenylcyclopropylamines. Part 5: Effects of electron-withdrawing or -donating aryl substituents on the inhibition of monoamine oxidases A and B by 2-aryl-2-fluoro-cyclopropylamines.
Hruschka S, Rosen TC, Yoshida S, Kirk KL, Fröhlich R, Wibbeling B, Haufe G.
Bioorg Med Chem (2008) 16 : 7148 -7166
PubMed 18640844 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.22 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL445285 1 8.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL445285 IC50 = 6.0 nM 8.22