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Assay Detail

CHEMBL975905

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Binding
Binding affinity to Serratia marcescens chitinase B
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Serratia marcescens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Chitinase B (CHEMBL5348)
Type SINGLE PROTEIN
Organism Serratia marcescens

Publication

Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens.
Gouda H, Yanai Y, Sugawara A, Sunazuka T, Omura S, Hirono S.
Bioorg Med Chem (2008) 16 : 3565 -3579
PubMed 18313305 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.74 8.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL445236 ARGADIN 1 8.47
CHEMBL197199 ARGIFIN 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL445236 ARGADIN IC50 = 3.4 nM 8.47
CHEMBL197199 ARGIFIN IC50 = 100.0 nM 7.00