Assay Detail
Functional
CHEMBL976209
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at adenosine A2B receptor in Wistar-Kyoto rat colon assessed as inhibition of bethanecol-induced contraction after 30 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Colon |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
1,3-dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 8.66 | 8.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL513681 | — | — | 1 | 8.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL513681 | — | Kd | = | 2.188 | nM | 8.66 |