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Assay Detail

CHEMBL976623

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Crotalus adamanteus venom phospholipase A2 by fluorometric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Crotalus adamanteus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Phospholipase A2 alpha (CHEMBL5711)
Type SINGLE PROTEIN
Organism Crotalus adamanteus

Publication

Hyrtiazepine, an azepino-indole-type alkaloid from the Red Sea marine sponge Hyrtios erectus.
Sauleau P, Martin MT, Dau ME, Youssef DT, Bourguet-Kondracki ML.
J Nat Prod (2006) 69 : 1676 -1679
PubMed 17190441 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.63 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL463914 MANOALIDE 1 6.40
CHEMBL465767 HYRTIOSULAWESINE 1 4.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL463914 MANOALIDE IC50 = 400.0 nM 6.40
CHEMBL465767 HYRTIOSULAWESINE IC50 = 14000.0 nM 4.85