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Assay Detail

CHEMBL977562

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human DLD1 cells by MTS colorimetric assay
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type DLD-1
Confidence 1 — Organism
Curated By Autocuration

Target

DLD-1 (CHEMBL614285)
Type CELL-LINE
Organism Homo sapiens

Publication

Cytotoxic constituents of Polyalthia longifolia var. pendula.
Chen CY, Chang FR, Shih YC, Hsieh TJ, Chia YC, Tseng HY, Chen HC, Chen SJ, Hsu MC, Wu YC.
J Nat Prod (2000) 63 : 1475 -1478
PubMed 11087586 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.54 4.54
Activity 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL401798 ANONAINE 1 4.54
CHEMBL486985 1 -
CHEMBL487389 1 -
CHEMBL520552 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL401798 ANONAINE IC50 = 28900.0 nM 4.54
CHEMBL486985 IC50 > 30000.0 nM -
CHEMBL487389 IC50 > 30000.0 nM -
CHEMBL520552 Activity - -