Assay Detail
Binding
CHEMBL979111
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Inhibition of human recombinant soluble adenylyl cyclase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-based development of novel adenylyl cyclase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.65 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1162355 | — | — | 1 | 6.16 |
| CHEMBL387152 | — | — | 1 | 5.96 |
| CHEMBL467987 | — | — | 1 | 5.52 |
| CHEMBL401844 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1162355 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL387152 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL467987 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL401844 | — | IC50 | = | 11000.0 | nM | 4.96 |