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Assay Detail

CHEMBL979307

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Binding
Inhibition of plasmin
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Plasminogen (CHEMBL1801)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Sesquiterpenoids and plasmin-inhibitory flavonoids from Blumea balsamifera.
Osaki N, Koyano T, Kowithayakorn T, Hayashi M, Komiyama K, Ishibashi M.
J Nat Prod (2005) 68 : 447 -449
PubMed 15787457 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.79 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL191881 LEUPEPTIN 1 5.92
CHEMBL164861 1 5.82
CHEMBL183745 1 5.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL191881 LEUPEPTIN IC50 = 1200.0 nM 5.92
CHEMBL164861 IC50 = 1500.0 nM 5.82
CHEMBL183745 IC50 = 2300.0 nM 5.64