Compound Detail
CHEMBL183745
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL183745 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RRRSSAVLTCVNIQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
300.3
MW (Da)
2.59
ALogP
6
HBA
3
HBD
100.1
PSA (Ų)
0.63
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasminogen CHEMBL1801 | IC50 | 5.64 | 5.64 | 2300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasminogen | IC50 | = | 2300.0 | nM | 5.64 | Inhibition of plasmin | 15787457 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29887353 | 10.1016/j.bmcl.2018.05.051 | B16 | 12 |
| 15603945 | 10.1016/j.bmcl.2004.10.081 | Molecular identity unknown | 1 |
| 15787457 | 10.1021/np049622e | Plasminogen | 1 |
| 37683361 | 10.1016/j.ejmech.2023.115791 | Transient receptor potential cation channel subfamily V member 1 | 1 |
| 37683361 | 10.1016/j.ejmech.2023.115791 | HaCaT | 1 |
| 37683361 | 10.1016/j.ejmech.2023.115791 | Neutrophil | 1 |
Data from ChEMBL 36 via Core Engine