Assay Detail
Functional
CHEMBL979670
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Cytotoxicity against rat H4IIE cells by XTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | H4IIE |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of furanonaphthoquinones with hydroxyamino side chains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.38 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL490499 | — | — | 1 | 5.70 |
| CHEMBL451308 | — | — | 1 | 5.70 |
| CHEMBL476506 | — | — | 1 | 5.70 |
| CHEMBL492156 | — | — | 1 | 5.40 |
| CHEMBL523457 | — | — | 1 | 5.30 |
| CHEMBL492825 | — | — | 1 | 5.30 |
| CHEMBL62539 | — | — | 1 | 5.30 |
| CHEMBL59970 | — | — | 1 | 5.16 |
| CHEMBL294323 | — | — | 1 | 4.82 |
| CHEMBL521769 | — | — | 1 | - |
| CHEMBL490336 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL490499 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL451308 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL476506 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL492156 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL523457 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL492825 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL62539 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL59970 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL294323 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL521769 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL490336 | — | IC50 | > | 20000.0 | nM | - |