Assay Detail
Binding
CHEMBL980280
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Inhibition of rat DNA polymerase beta in absence of BSA
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
DNA polymerase beta inhibitors from Baeckea gunniana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.46 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL479472 | — | — | 1 | 5.60 |
| CHEMBL517522 | — | — | 1 | 5.50 |
| CHEMBL168 | OLEANOLIC_ACID | — | 1 | 5.43 |
| CHEMBL169 | URSOLIC ACID | 2.0 | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL479472 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL517522 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL168 | OLEANOLIC_ACID | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL169 | URSOLIC ACID | IC50 | = | 4800.0 | nM | 5.32 |