Assay Detail
Binding
CHEMBL980283
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Inhibition of rat DNA polymerase beta in presence of 0.1 mg/mL BSA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
DNA polymerase beta inhibitors from Tetracera boiviniana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.02 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL453751 | — | — | 1 | 5.38 |
| CHEMBL269277 | BETULINIC ACID | 1.0 | 1 | 4.85 |
| CHEMBL463995 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL453751 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL269277 | BETULINIC ACID | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL463995 | — | IC50 | = | 15000.0 | nM | 4.82 |