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Assay Detail

CHEMBL980362

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to 5HT2A
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

5-hydroxytryptamine receptor 2A (CHEMBL224)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent advances in selective alpha1-adrenoreceptor antagonists as antihypertensive agents.
Jain KS, Bariwal JB, Kathiravan MK, Phoujdar MS, Sahne RS, Chauhan BS, Shah AK, Yadav MR.
Bioorg Med Chem (2008) 16 : 4759 -4800
PubMed 18378462 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.72 8.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL514848 1 8.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL514848 Ki = 1.92 nM 8.72