Assay Detail
Binding
CHEMBL980942
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Inhibition of pig erythrocyte mu-calpain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and calpain inhibitory activity of peptidomimetic compounds with constrained amino acids at the P2 position.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.51 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL513049 | — | — | 1 | 7.10 |
| CHEMBL304784 | — | — | 1 | 6.72 |
| CHEMBL470973 | — | — | 1 | 5.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL513049 | — | Ki | = | 80.0 | nM | 7.10 |
| CHEMBL304784 | — | Ki | = | 190.0 | nM | 6.72 |
| CHEMBL470973 | — | Ki | = | 1940.0 | nM | 5.71 |