Assay Detail
Functional
CHEMBL983166
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Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells by Griess method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Saponins from Cussonia bancoensis and their inhibitory effects on nitric oxide production.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.72 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL523622 | — | — | 1 | 5.58 |
| CHEMBL7889 | L-NIL | — | 1 | 4.73 |
| CHEMBL461104 | — | — | 1 | 4.66 |
| CHEMBL169 | URSOLIC ACID | 2.0 | 1 | 4.33 |
| CHEMBL506997 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL523622 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL7889 | L-NIL | IC50 | = | 18600.0 | nM | 4.73 |
| CHEMBL461104 | — | IC50 | = | 22100.0 | nM | 4.66 |
| CHEMBL169 | URSOLIC ACID | IC50 | = | 46900.0 | nM | 4.33 |
| CHEMBL506997 | — | IC50 | = | 47900.0 | nM | 4.32 |