Assay Detail
Functional
CHEMBL983176
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 infected in human H9 cells assessed as effect on virus-induced cytopathic effect by tetrazolium/formazan assay
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
New pyranocoumarins isolated from Calophyllum lanigerum and Calophyllum teysmannii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 4 | - | - |
| EC50 | 2 | 6.11 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL7187 | COSTATOLIDE | — | 1 | 6.66 |
| CHEMBL518356 | CALANOLIDE F | — | 1 | 5.55 |
| CHEMBL92735 | CALANOLIDE E2 | — | 1 | - |
| CHEMBL462675 | — | — | 1 | - |
| CHEMBL507953 | PSEUDOCARDATOLIDE C | — | 1 | - |
| CHEMBL462029 | CORDATOLIDE E | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL7187 | COSTATOLIDE | EC50 | = | 220.0 | nM | 6.66 |
| CHEMBL518356 | CALANOLIDE F | EC50 | = | 2840.0 | nM | 5.55 |
| CHEMBL92735 | CALANOLIDE E2 | Activity | - | — | - | |
| CHEMBL462675 | — | Activity | - | — | - | |
| CHEMBL507953 | PSEUDOCARDATOLIDE C | Activity | - | — | - | |
| CHEMBL462029 | CORDATOLIDE E | Activity | - | — | - |