Assay Detail
Binding
CHEMBL983400
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Inhibition of Saccharomyces sp. alpha-glucosidase
15
Total Activities
15
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces sp. |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
alpha-Glucosidase inhibitory activity of triterpenoids from Cichorium intybus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 10 | - | - |
| IC50 | 5 | 4.48 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL506936 | — | — | 1 | 5.00 |
| CHEMBL466142 | — | — | 1 | 4.29 |
| CHEMBL120568 | VANILLIC ACID | — | 1 | 4.16 |
| CHEMBL513679 | — | — | 1 | - |
| CHEMBL467773 | — | — | 1 | - |
| CHEMBL244743 | ESCULETIN | — | 1 | - |
| CHEMBL1414 | SYRINGIC ACID | — | 1 | - |
| CHEMBL512622 | BETULINALDEHYDE | — | 1 | - |
| CHEMBL23236 | BETULIN | — | 1 | - |
| CHEMBL269277 | BETULINIC ACID | 1.0 | 1 | - |
| CHEMBL400247 | STIGMASTEROL | — | 1 | - |
| CHEMBL221542 | BETA-SITOSTEROL | — | 1 | - |
| CHEMBL289191 | LUPEOL | — | 1 | - |
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | - |
| CHEMBL485998 | FRIEDELINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL506936 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL466142 | — | IC50 | = | 51900.0 | nM | 4.29 |
| CHEMBL120568 | VANILLIC ACID | IC50 | = | 69000.0 | nM | 4.16 |
| CHEMBL513679 | — | Activity | - | — | - | |
| CHEMBL467773 | — | Activity | - | — | - | |
| CHEMBL244743 | ESCULETIN | Activity | - | — | - | |
| CHEMBL1414 | SYRINGIC ACID | Activity | - | — | - | |
| CHEMBL512622 | BETULINALDEHYDE | Activity | - | — | - | |
| CHEMBL23236 | BETULIN | Activity | - | — | - | |
| CHEMBL269277 | BETULINIC ACID | Activity | - | — | - | |
| CHEMBL400247 | STIGMASTEROL | Activity | - | — | - | |
| CHEMBL221542 | BETA-SITOSTEROL | Activity | - | — | - | |
| CHEMBL289191 | LUPEOL | Activity | - | — | - | |
| CHEMBL307429 | DUVOGLUSTAT | IC50 | = | 425000.0 | nM | - |
| CHEMBL485998 | FRIEDELINE | IC50 | = | 321000.0 | nM | - |