Assay Detail
ADMET
CHEMBL983574
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against HEK293 cells by MTT assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 4.10 | 4.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1162373 | — | — | 1 | 4.10 |
| CHEMBL3138459 | — | — | 1 | 4.10 |
| CHEMBL205596 | CHOLIC ACID | 4.0 | 1 | - |
| CHEMBL443511 | — | — | 1 | - |
| CHEMBL500877 | — | — | 1 | - |
| CHEMBL1162374 | — | — | 1 | - |
| CHEMBL3138441 | — | — | 1 | - |
| CHEMBL444443 | — | — | 1 | - |
| CHEMBL502442 | — | — | 1 | - |
| CHEMBL1162375 | — | — | 1 | - |
| CHEMBL504113 | — | — | 1 | - |
| CHEMBL1162376 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1162373 | — | IC50 | = | 80000.0 | nM | 4.10 |
| CHEMBL3138459 | — | IC50 | = | 80000.0 | nM | 4.10 |
| CHEMBL205596 | CHOLIC ACID | IC50 | > | 1000000.0 | nM | - |
| CHEMBL443511 | — | IC50 | = | 600000.0 | nM | - |
| CHEMBL500877 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL1162374 | — | IC50 | = | 700000.0 | nM | - |
| CHEMBL3138441 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL444443 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL502442 | — | IC50 | = | 200000.0 | nM | - |
| CHEMBL1162375 | — | IC50 | = | 800000.0 | nM | - |
| CHEMBL504113 | — | IC50 | = | 800000.0 | nM | - |
| CHEMBL1162376 | — | IC50 | = | 800000.0 | nM | - |