Assay Detail
Binding
CHEMBL983873
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Displacement of [3H]SCH23390 from dopamine D1 receptor in rat corpus striatum
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and binding studies of 2-O- and 11-O-substituted N-alkylnoraporphines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.81 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27559 | — | — | 1 | 6.16 |
| CHEMBL520262 | — | — | 1 | 5.89 |
| CHEMBL480525 | — | — | 1 | 5.74 |
| CHEMBL520573 | — | — | 1 | 5.43 |
| CHEMBL480149 | — | — | 1 | - |
| CHEMBL480526 | — | — | 1 | - |
| CHEMBL480524 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27559 | — | Ki | = | 699.0 | nM | 6.16 |
| CHEMBL520262 | — | Ki | = | 1300.0 | nM | 5.89 |
| CHEMBL480525 | — | Ki | = | 1810.0 | nM | 5.74 |
| CHEMBL520573 | — | Ki | = | 3680.0 | nM | 5.43 |
| CHEMBL480149 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL480526 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL480524 | — | Ki | > | 10000.0 | nM | - |