Assay Detail
Binding
CHEMBL983875
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Displacement of [3H]8-OH-DPAT from Serotonin 5-HT1A receptor in rat corpus striatum
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and binding studies of 2-O- and 11-O-substituted N-alkylnoraporphines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.07 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL480526 | — | — | 1 | 6.54 |
| CHEMBL520573 | — | — | 1 | 6.37 |
| CHEMBL480524 | — | — | 1 | 5.80 |
| CHEMBL520262 | — | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL480526 | — | Ki | = | 289.0 | nM | 6.54 |
| CHEMBL520573 | — | Ki | = | 432.0 | nM | 6.37 |
| CHEMBL480524 | — | Ki | = | 1600.0 | nM | 5.80 |
| CHEMBL520262 | — | Ki | = | 2660.0 | nM | 5.58 |