Assay Detail
Binding
CHEMBL984137
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Binding affinity to p38alpha by exchange curve binding kinetic analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 9.37 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL103667 | DORAMAPIMOD | 2.0 | 1 | 10.00 |
| CHEMBL523978 | — | — | 1 | 8.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL103667 | DORAMAPIMOD | Kd | = | 0.1 | nM | 10.00 |
| CHEMBL523978 | — | Kd | = | 1.8 | nM | 8.74 |