Assay Detail
Functional
CHEMBL984430
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Antiviral activity against Reo virus 1 infected in BHK21 cells assessed as protection against virus-induced cytopathogenicity after 4 days by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mammalian orthoreovirus 1 |
| Cell Type | BHK-21 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimicrobial and cytotoxic arylazoenamines. Part III: antiviral activity of selected classes of arylazoenamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.36 | 4.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL476974 | — | — | 1 | 4.50 |
| CHEMBL502222 | — | — | 1 | 4.47 |
| CHEMBL477177 | — | — | 1 | 4.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL476974 | — | EC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL502222 | — | EC50 | = | 34000.0 | nM | 4.47 |
| CHEMBL477177 | — | EC50 | = | 76000.0 | nM | 4.12 |