Assay Detail
Binding
CHEMBL985097
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of COX1 in human whole blood assessed as TXB2 production by enzyme immunoassay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel 6-methanesulfonamide-3,4-methylenedioxyphenyl-N-acylhydrazones: orally effective anti-inflammatory drug candidates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.18 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL482199 | — | — | 1 | 5.39 |
| CHEMBL56367 | NIMESULIDE | 4.0 | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL482199 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL56367 | NIMESULIDE | IC50 | = | 10900.0 | nM | 4.96 |