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Assay Detail

CHEMBL986505

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of EGFR by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Epidermal growth factor receptor (CHEMBL203)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Naturally occurring homoisoflavonoids function as potent protein tyrosine kinase inhibitors by c-Src-based high-throughput screening.
Lin LG, Xie H, Li HL, Tong LJ, Tang CP, Ke CQ, Liu QF, Lin LP, Geng MY, Jiang H, Zhao WM, Ding J, Ye Y.
J Med Chem (2008) 51 : 4419 -4429
PubMed 18610999 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.47 5.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL477197 HEMATOXYLIN 1 5.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL477197 HEMATOXYLIN IC50 = 3400.0 nM 5.47