Assay Detail
ADMET
CHEMBL987291
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Growth inhibition of human HCEC after 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HCEC |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Functionalized pyrrolidine inhibitors of human type II alpha-mannosidases as anti-cancer agents: optimizing the fit to the active site.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 2 | - | - |
| IC50 | 1 | 4.00 | 4.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL476343 | — | — | 1 | 4.00 |
| CHEMBL476925 | — | — | 1 | - |
| CHEMBL476926 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL476343 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL476925 | — | Activity | - | — | - | |
| CHEMBL476926 | — | Activity | - | — | - |