Assay Detail
Functional
CHEMBL988362
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Antiproliferative activity against T cells
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | T-cell |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of conformationally rigid 3-azabicyclo[3.1.0]hexane-derived dipeptidyl peptidase-IV inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 6.08 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL505629 | — | — | 1 | 6.08 |
| CHEMBL479567 | — | — | 1 | - |
| CHEMBL452998 | — | — | 1 | - |
| CHEMBL471956 | — | — | 1 | - |
| CHEMBL511125 | — | — | 1 | - |
| CHEMBL479538 | — | — | 1 | - |
| CHEMBL471785 | — | — | 1 | - |
| CHEMBL471784 | — | — | 1 | - |
| CHEMBL480155 | — | — | 1 | - |
| CHEMBL480914 | — | — | 1 | - |
| CHEMBL142703 | VILDAGLIPTIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL505629 | — | IC50 | = | 839.0 | nM | 6.08 |
| CHEMBL479567 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL452998 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL471956 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL511125 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL479538 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL471785 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL471784 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL480155 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL480914 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL142703 | VILDAGLIPTIN | IC50 | > | 10000.0 | nM | - |