Assay Detail
Functional
CHEMBL988428
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplatelet activity against rabbit platelet assessed as inhibition of collagen-induced platelet aggregation preincubated for 3 mins by turbidimetric method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Cell Type | Platelet |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiplatelet flavonoids from seeds of Psoralea corylifolia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.31 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25 | ASPIRIN | 4.0 | 1 | 4.52 |
| CHEMBL512693 | NEOBAVAISOFLAVONE | — | 1 | 4.21 |
| CHEMBL253467 | ISOBAVACHALCONE | — | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25 | ASPIRIN | IC50 | = | 30500.0 | nM | 4.52 |
| CHEMBL512693 | NEOBAVAISOFLAVONE | IC50 | = | 62400.0 | nM | 4.21 |
| CHEMBL253467 | ISOBAVACHALCONE | IC50 | = | 65100.0 | nM | 4.19 |