Assay Detail
Binding
CHEMBL988942
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human MARK1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase MARK1 (CHEMBL5940) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Assessment of chemical coverage of kinome space and its implications for kinase drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.82 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL408019 | — | — | 1 | 6.68 |
| CHEMBL511337 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL408019 | — | Kd | = | 207.0 | nM | 6.68 |
| CHEMBL511337 | — | Kd | = | 11000.0 | nM | 4.96 |