Assay Detail
Functional
CHEMBL989249
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity against mouse CCK1 receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Gastrin/cholecystokinin type B receptor (CHEMBL2854) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Discovery of imidazole carboxamides as potent and selective CCK1R agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 9.15 | 9.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL505969 | — | — | 1 | 9.85 |
| CHEMBL446789 | — | — | 1 | 9.52 |
| CHEMBL443189 | — | — | 1 | 9.11 |
| CHEMBL505409 | — | — | 1 | 8.89 |
| CHEMBL506201 | — | — | 1 | 8.82 |
| CHEMBL503822 | — | — | 1 | 8.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL505969 | — | EC50 | = | 0.14 | nM | 9.85 |
| CHEMBL446789 | — | EC50 | = | 0.3 | nM | 9.52 |
| CHEMBL443189 | — | EC50 | = | 0.78 | nM | 9.11 |
| CHEMBL505409 | — | EC50 | = | 1.3 | nM | 8.89 |
| CHEMBL506201 | — | EC50 | = | 1.5 | nM | 8.82 |
| CHEMBL503822 | — | EC50 | = | 2.1 | nM | 8.68 |