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Assay Detail

CHEMBL989802

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of sPLA2 group 10
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Group 10 secretory phospholipase A2 (CHEMBL4342)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA.
Oslund RC, Cermak N, Verlinde CL, Gelb MH.
Bioorg Med Chem Lett (2008) 18 : 5415 -5419
PubMed 18818074 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL444450 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL444450 IC50 = 200.0 nM 6.70