Assay Detail
Functional
CHEMBL990231
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Simian immunodeficiency virus
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Simian immunodeficiency virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Simian immunodeficiency virus (CHEMBL613499) ↗| Type | ORGANISM |
| Organism | Simian immunodeficiency virus |
Publication
The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A and B, and acid-hydrolysis products of chloropeptin I.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL506605 | ISOCOMPLESTATIN | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL506605 | ISOCOMPLESTATIN | IC50 | = | 100.0 | nM | 7.00 |