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CHEMBL613499 Target Snapshot
Simian immunodeficiency virus · ORGANISM · Simian immunodeficiency virus
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Simian immunodeficiency virus
Review this target as Simian immunodeficiency virus.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Simian immunodeficiency virus as ChEMBL target CHEMBL613499. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Simian immunodeficiency virus |
| Target Type | ORGANISM |
| Organism | Simian immunodeficiency virus |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Simian immunodeficiency virus |
| UniProt Accession | N/A |
Simian immunodeficiency virus
How to read this target
Review this target as Simian immunodeficiency virus.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL129 | 9.3 | IC50 | 0.5 | Approved |
| CHEMBL129 | 7.96 | EC50 | 11.0 | Approved |
| CHEMBL331237 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL584 | 7.3 | EC50 | 50.0 | Approved |
| CHEMBL506605 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL512498 | 7.0 | EC50 | 100.0 | Preclinical |
| CHEMBL497246 | 6.77 | EC50 | 170.0 | Preclinical |
| CHEMBL601493 | 6.77 | EC50 | 170.0 | Preclinical |
| CHEMBL390811 | 6.7 | EC50 | 200.0 | Preclinical |
| CHEMBL511803 | 6.7 | EC50 | 200.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Functional — 31 assays, 220 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 30 | 220 | 5.5 |
| assay format | 1 | 0 | — |
ADME — 1 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 1 | 0 | — |