Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL613499 Target Snapshot

Simian immunodeficiency virus · ORGANISM · Simian immunodeficiency virus

312Compounds
32Assays
3Approved Drugs
321.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Simian immunodeficiency virus as ChEMBL target CHEMBL613499. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Simian immunodeficiency virus
ORGANISM · Simian immunodeficiency virus
As of 2026-09-14
ChEMBL target ID
CHEMBL613499
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Simian immunodeficiency virus still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSimian immunodeficiency virus
UniProt AccessionN/A

Simian immunodeficiency virus

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Simian immunodeficiency virus.

Review nameSimian immunodeficiency virus
OrganismSimian immunodeficiency virus
Clinical Profile

Clinical Phase Distribution

3
Approved
1
Phase III
Assay Mix

Activity Type Distribution

IC5083.0
EC50238.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL129 9.3 IC50 0.5 Approved
CHEMBL129 7.96 EC50 11.0 Approved
CHEMBL331237 7.4 IC50 40.0 Preclinical
CHEMBL584 7.3 EC50 50.0 Approved
CHEMBL506605 7.0 IC50 100.0 Preclinical
CHEMBL512498 7.0 EC50 100.0 Preclinical
CHEMBL497246 6.77 EC50 170.0 Preclinical
CHEMBL601493 6.77 EC50 170.0 Preclinical
CHEMBL390811 6.7 EC50 200.0 Preclinical
CHEMBL511803 6.7 EC50 200.0 Preclinical
Distribution

pChEMBL Value Distribution

117
5.0
40
5.5
25
6.0
9
6.5
5
7.0
2
7.5
1
8.0
0
8.5
1
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

NELFINAVIR
CHEMBL584
Approved 1997
ZIDOVUDINE
CHEMBL129
Approved 1987
Assay Landscape

Assay Landscape

32
Total Assays
220
Tested Compounds
2
Assay Types
Functional — 31 assays, 220 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 30 220 5.5
assay format 1 0
ADME — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine