Assay Detail
Functional
CHEMBL990605
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at TLR4 in human HL60 cells assessed as inhibition of LPS-induced cytokine production
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small molecule modulators of toll-like receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.82 | 8.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3301672 | ERITORAN TETRASODIUM | 3.0 | 1 | 8.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3301672 | ERITORAN TETRASODIUM | IC50 | = | 1.5 | nM | 8.82 |