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Assay Detail

CHEMBL991180

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Binding
Inhibition of cow milk xanthine oxidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Xanthine dehydrogenase/oxidase (CHEMBL3649)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Pentagalloylglucose, a xanthine oxidase inhibitor from a Paraguayan crude drug, "Molle-i" (Schinus terebinthifolius).
Hayashi T, Nagayama K, Arisawa M, Shimizu M, Suzuki S, Yoshizaki M, Morita N, Ferro E, Basualdo I, Berganza LH.
J Nat Prod (1989) 52 : 210 -211
PubMed 2723668 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.65 5.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1467 ALLOPURINOL 4.0 1 5.80
CHEMBL382408 PENTAGALLOYL GLUCOSE 1 5.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1467 ALLOPURINOL IC50 = 1600.0 nM 5.80
CHEMBL382408 PENTAGALLOYL GLUCOSE IC50 = 3200.0 nM 5.50