Assay Detail
Functional
CHEMBL991222
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Cytotoxicity against human HCT116 cells by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Sesquiterpenoids from Artemisia gilvescens and an anti-MRSA compound.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.08 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL513501 | SECOTANAPARTHOLIDE B | — | 1 | 5.48 |
| CHEMBL446076 | SECOTANAPARTHOLIDE A | — | 1 | 5.22 |
| CHEMBL467620 | — | — | 1 | 5.22 |
| CHEMBL508537 | ISOSECOTANAPARTHOLIDE | — | 1 | 4.89 |
| CHEMBL271164 | ARTECANIN | — | 1 | 4.85 |
| CHEMBL509212 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL513501 | SECOTANAPARTHOLIDE B | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL446076 | SECOTANAPARTHOLIDE A | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL467620 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL508537 | ISOSECOTANAPARTHOLIDE | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL271164 | ARTECANIN | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL509212 | — | IC50 | = | 16000.0 | nM | 4.80 |