Assay Detail
Binding
CHEMBL991567
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Inhibition of pig kidney m-calpain
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Molecular design to enhance the penetration into the retina via ocular instillation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.88 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL478222 | — | — | 1 | 7.00 |
| CHEMBL475920 | — | — | 1 | 7.00 |
| CHEMBL516123 | — | — | 1 | 6.92 |
| CHEMBL473251 | — | — | 1 | 6.77 |
| CHEMBL455277 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL478222 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL475920 | — | IC50 | = | 99.0 | nM | 7.00 |
| CHEMBL516123 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL473251 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL455277 | — | IC50 | = | 190.0 | nM | 6.72 |