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Assay Detail

CHEMBL991620

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against cisplatin-resistant human C13 cells after 48 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type C13
Confidence 1 — Organism
Curated By Autocuration

Publication

Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.
Cozza G, Gianoncelli A, Montopoli M, Caparrotta L, Venerando A, Meggio F, Pinna LA, Zagotto G, Moro S.
Bioorg Med Chem Lett (2008) 18 : 5672 -5675
PubMed 18799313 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.58 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL88326 1 5.10
CHEMBL86771 1 4.06

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL88326 IC50 = 8000.0 nM 5.10
CHEMBL86771 IC50 = 87900.0 nM 4.06