Assay Detail
Functional
CHEMBL992088
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at ERbeta by fluorescence polarization assay
8
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Pochonins A-F, new antiviral and antiparasitic resorcylic acid lactones from Pochonia chlamydosporia var. catenulata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 7.10 | 7.72 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL499812 | — | — | 1 | 7.72 |
| CHEMBL450613 | ZERANOL | 2.0 | 1 | 7.62 |
| CHEMBL491499 | ZEARALANONE | — | 2 | 7.42 |
| CHEMBL491510 | TALERANOL | 2.0 | 2 | 7.14 |
| CHEMBL454173 | ZEARALENONE | — | 1 | 6.96 |
| CHEMBL465785 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL499812 | — | EC50 | = | 19.0 | nM | 7.72 |
| CHEMBL450613 | ZERANOL | EC50 | = | 24.0 | nM | 7.62 |
| CHEMBL491499 | ZEARALANONE | EC50 | = | 38.0 | nM | 7.42 |
| CHEMBL491510 | TALERANOL | EC50 | = | 72.0 | nM | 7.14 |
| CHEMBL454173 | ZEARALENONE | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL491510 | TALERANOL | EC50 | = | 220.0 | nM | 6.66 |
| CHEMBL491499 | ZEARALANONE | EC50 | = | 660.0 | nM | 6.18 |
| CHEMBL465785 | — | Activity | - | — | - |