Assay Detail
Functional
CHEMBL992106
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Growth inhibition of mouse Hepa-1c1c7 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Hepa-1c1c7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.40 | 4.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129795 | ISOLIQUIRITIGENIN | — | 1 | 4.56 |
| CHEMBL48802 | SULFORAPHANE | 3.0 | 1 | 4.56 |
| CHEMBL446827 | — | — | 1 | 4.46 |
| CHEMBL468666 | — | — | 1 | 4.31 |
| CHEMBL490355 | SULFURETIN | — | 1 | 4.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129795 | ISOLIQUIRITIGENIN | IC50 | = | 27300.0 | nM | 4.56 |
| CHEMBL48802 | SULFORAPHANE | IC50 | = | 27300.0 | nM | 4.56 |
| CHEMBL446827 | — | IC50 | = | 34600.0 | nM | 4.46 |
| CHEMBL468666 | — | IC50 | = | 48500.0 | nM | 4.31 |
| CHEMBL490355 | SULFURETIN | IC50 | = | 78500.0 | nM | 4.11 |