Assay Detail
Functional
CHEMBL992383
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Cytotoxicity against human CFUGM
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CFU-GM |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive peroxides as potential therapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.16 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL526138 | ARTEMISITENE | — | 1 | 5.77 |
| CHEMBL443124 | — | — | 1 | 5.44 |
| CHEMBL498923 | — | — | 1 | 4.28 |
| CHEMBL269671 | ARTEMISININ | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL526138 | ARTEMISITENE | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL443124 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL498923 | — | IC50 | = | 52500.0 | nM | 4.28 |
| CHEMBL269671 | ARTEMISININ | IC50 | = | 385000.0 | nM | - |