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Assay Detail

CHEMBL992385

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse Ehrlich Ascites carcinoma by MMT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 1 — Organism
Curated By Autocuration

Publication

Bioactive peroxides as potential therapeutic agents.
Dembitsky VM.
Eur J Med Chem (2008) 43 : 223 -251
PubMed 17618015 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.97 5.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL443124 1 5.44
CHEMBL526138 ARTEMISITENE 1 4.95
CHEMBL498923 1 4.51
CHEMBL269671 ARTEMISININ 3.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL443124 IC50 = 3600.0 nM 5.44
CHEMBL526138 ARTEMISITENE IC50 = 11300.0 nM 4.95
CHEMBL498923 IC50 = 31200.0 nM 4.51
CHEMBL269671 ARTEMISININ IC50 > 723000.0 nM -