Assay Detail
ADMET
CHEMBL992735
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Cytotoxicity against human HeLa Ohio-1 cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Cinnamoyl- and hydroxycinnamoyl amides of glaucine and their antioxidative and antiviral activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.17 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL470881 | OXOGLAUCINE | — | 1 | 6.52 |
| CHEMBL283639 | DISOXARIL | 2.0 | 1 | 5.82 |
| CHEMBL454215 | — | — | 1 | 4.92 |
| CHEMBL478396 | — | — | 1 | 4.89 |
| CHEMBL479025 | — | — | 1 | 4.82 |
| CHEMBL228082 | GLAUCINE | — | 1 | 4.66 |
| CHEMBL505809 | — | — | 1 | 4.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL470881 | OXOGLAUCINE | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL283639 | DISOXARIL | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL454215 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL478396 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL479025 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL228082 | GLAUCINE | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL505809 | — | IC50 | = | 28000.0 | nM | 4.55 |