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Assay Detail

CHEMBL993537

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [11C]DAA1106 from PBR receptor in rat brain membrane
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Brain
Subcellular Membrane
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Translocator protein (CHEMBL4552)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

[18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain.
Yanamoto K, Kumata K, Yamasaki T, Odawara C, Kawamura K, Yui J, Hatori A, Suzuki K, Zhang MR.
Bioorg Med Chem Lett (2009) 19 : 1707 -1710
PubMed 19217778 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 10.10 10.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL292092 1 10.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL292092 Ki = 0.08 nM 10.10