Assay Detail
Binding
CHEMBL993538
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [11C]flumazenil from CBR receptor in rat brain membrane
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
[18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.08 | 5.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL476607 | — | — | 1 | 5.08 |
| CHEMBL515622 | — | — | 1 | - |
| CHEMBL476811 | — | — | 1 | - |
| CHEMBL513922 | EMAPUNIL | 2.0 | 1 | - |
| CHEMBL481537 | PK-11195 | — | 1 | - |
| CHEMBL292092 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL476607 | — | Ki | = | 8400.0 | nM | 5.08 |
| CHEMBL515622 | — | Ki | > | 8400.0 | nM | - |
| CHEMBL476811 | — | Ki | > | 8400.0 | nM | - |
| CHEMBL513922 | EMAPUNIL | Ki | > | 8400.0 | nM | - |
| CHEMBL481537 | PK-11195 | Ki | > | 8400.0 | nM | - |
| CHEMBL292092 | — | Ki | > | 1000.0 | nM | - |