Compound Detail
CHEMBL515622
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Basic Information
| ChEMBL ID | CHEMBL515622 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DCRSPOGUAKBGJJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
433.5
MW (Da)
3.28
ALogP
6
HBA
0
HBD
73.0
PSA (Ų)
0.43
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.31
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Translocator protein CHEMBL4552 | Ki | 9.31 | 9.31 | 0.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Translocator protein | Ki | = | 0.49 | nM | 9.31 | Displacement of [11C]PK11195 from PBR receptor in rat brain membrane | 19217778 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19217778 | 10.1016/j.bmcl.2009.01.093 | Translocator protein | 1 |
| 19217778 | 10.1016/j.bmcl.2009.01.093 | Unchecked | 1 |
| 19217778 | 10.1016/j.bmcl.2009.01.093 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine