Assay Detail
Functional
CHEMBL994122
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Phototoxicity against human HL60 cells on exposure to 13.3 J/cm'2 light after 16 hrs by Trypan blue exclusion method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Glycol porphyrin derivatives as potent photodynamic inducers of apoptosis in tumor cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.38 | 7.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL500576 | TEMOPORFIN | 4.0 | 1 | 7.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL500576 | TEMOPORFIN | IC50 | = | 42.0 | nM | 7.38 |